To study the curative effect of laparoscopic and open radical gastrectomy in the treatment of gastric cancer.

98 cases of gastric cancer from March 2012 to March 2017 were retrospectively analyzed. According to the different surgical methods, 98 patients were divided into open group and laparoscopic group, 49 cases in each group.The statistical analysis was done by SPSS19.0, the measurement index was described by (±s), the group t test was used to compare the data among groups, and the count data was analyzed by χ² test.

The length of incision, the time of anal exhaust, the time of getting out of bed, the time of extubation of drainage tube and the time of hospitalization were shorter in the laparoscopic group than in the open group. The amount of bleeding during operation and the times of using painkillers in the laparoscopy group were less than those in the open group, but the operative time was longer than that in the open group (P<0.05). There was no significant difference in the number of dissected lymph nodes and the distance from the distal end to the tumor between the two groups (P>0.05). The levels of CRP TNF-α and IL-6 increased 3 days after operation in both groups, and CRP in laparoscopic group. The levels of TNF-α and IL-6 were lower than those in the open group (P<0.05), and the levels of no and et in the open group were higher than those in the preoperative group and the laparoscopic group (P<0.05). There was no significant difference in no and et levels between the laparoscopic group and the preoperative group (P>0.05). The postoperative complication rate was 6.12% in the laparoscopic group and 18.4% in the open group (P <0.05).

Laparoscopic radical resection of gastric cancer has the characteristics of short operation time , small incision , small stress response and fast recovery , and has less influence on the immune function of the organism .