To compare safety and efficacy of the laparoscopy and laparotomy on the treatment of advanced distal gastric carcinoma.

94 advanced gastric carcinoma patients from January 2015 to January 2017 in our hospital were retrospectively collected and were divided into one observation group and one control group, 47 patients each group. The patients in the observation group received laparoscopy-assisted radical gastrectomy for distal gastric carcinoma while the ones in the control group received laparotomy-assisted radical gastrectomy for distal gastric carcinoma, and all patients were followed-up 1 year. Operation condition, postoperative rehabilitation and clinical outcomes of the patients in both groups were observed. SPSS22.0 was used for statistical analysis, The intraoperative and postoperative indexes and AngII level in the two groups were expressed by(±s), T test of independent samples was used; Postoperative complications were examined by ray test, The difference was statistically significant (P<0.05).

The intraoperative blood loss in the observation group was significantly less than that in the control group, and the difference was statistically significant (P=0.000); There was no significant difference in preoperative AngII and CRP between the two groups (P>0.05), After 24 h, the indexes of stress reaction AngII and CRP in the observation group were significantly lower than those in the control group (P=0.000). Compared with the control group, the anal exhaust time of the observation group was significantly shortened (P=0.000), and the length of hospital stay was significantly shortened (P=0.000), The postoperative drainage time was significantly shortened (P=0.017), and the flow rate was significantly shortened (P=0.009). The total incidence of complications in the observation group was significantly lower than that in the control group, the difference was statistically significant (P=0.014). The operation time, the number of lymph node dissection, mortality and recurrence rate were not significantly different between the two groups (P>0.05).

Laparoscopic distal gastrectomy is safe and effective, which can significantly reduce postoperative stress response, reduce postoperative complications, and accelerate postoperative rehabilitation.