To compare the clinical outcome of 3D and 2D laparoscopic distal gastrectomy for patients with gastric cancer, and to explore the feasibility and safety of 3D laparoscopy.

From January 2015 and June 2017, 68 patients diagnosed with advanced stomach cancer were enrolled in our hospital, including 34 cases in 3D group and 34 cases in 2D group. were compared between the two groups. Statistical analysis were performed by using SPSS18.0 software. Intraoperative and postoperative clinical indicators and quality of life score were presented as mean±standard deviation, and were examined by using t test; The postoperative survival and complication rate were compared with χ² or Fisher test. P<0.05 was thought to be statistically significant.

Compared with 2D group, there were less intraoperative bleeding and more harvested lymph nodes in 3D group, with significant differences (P<0.05). There were no significant differences between 2 groups in terms of exhaust time and liquid nurtrion recovery time, proximal and distal dissection margin, the postoperative hospital stay, and postoperative complications, as well as the EORTC QLQST022 score 6 month after surgery and 1- and 2-year survival rate (P>0.05).

3D laparoscopic assisted D2 gastric cancer radical surgery is convenient to the surgeons, which could reduce the intraoperative blood loss and increase the number of removed lymph nodes. Besides, it does not increase postoperative complications as well as reduce life quality and survival rate, which is worth popularizing in clinical use.