切换至 "中华医学电子期刊资源库"

中华普外科手术学杂志(电子版) ›› 2025, Vol. 19 ›› Issue (02) : 153 -156. doi: 10.3877/cma.j.issn.1674-3946.2025.02.011.

论著

头尾侧联合入路腹腔镜右半结肠癌根治术的近中期临床观察
陈宝鹤1,(), 张文卓1, 王隽1   
  1. 1.221000 江苏徐州,徐州市中医院胃肠外科
  • 收稿日期:2023-12-04 出版日期:2025-04-26
  • 通信作者: 陈宝鹤
  • 基金资助:
    2020年度省中医药科技发展计划项目(YB2020066)2022年度省老年健康科研项目(LKM2022070)

Clinical observation of proximal and medium-term laparoscopic radical resection of right half colon cancer by combined cephalocaudal approach

Baohe Chen,1(), Wenzhuo Zhang1, Jun Wang1   

  1. 1.Department of Gastroenterology, Xuzhou Traditional Chinese Medicine Hospital, Xuzhou Jiangsu Province 221000, China
  • Received:2023-12-04 Published:2025-04-26
  • Corresponding author: Baohe Chen
引用本文:

陈宝鹤, 张文卓, 王隽. 头尾侧联合入路腹腔镜右半结肠癌根治术的近中期临床观察[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(02): 153-156.

Baohe Chen, Wenzhuo Zhang, Jun Wang. Clinical observation of proximal and medium-term laparoscopic radical resection of right half colon cancer by combined cephalocaudal approach[J/OL]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2025, 19(02): 153-156.

目的

探讨头尾侧联合入路腹腔镜右半结肠癌根治术的近中期疗效。

方法

回顾性分析2018年8月至2021年8月99例行腹腔镜根治术的右半结肠癌患者资料,根据入路不同分为头侧组(n=49例,行全头侧入路)和联合组(n=50例,行头尾侧联合入路)。采用SPSS 25.0软件处理数据,手术相关指标、术后恢复指标等计量资料以(± s)表示,采用独立样本t检验;并发症、生存率等计数资料用[例(%)]表示,采用χ2检验。P<0.05为差异有统计学意义。

结果

联合组患者手术时间较头侧组短,术中出血量、术中血管损伤例数较头侧组少(P<0.05);两组患者术后首次排气时间、首次进食时间、拔除引流管时间和住院时间比较,差异无统计学意义(P>0.05);两组患者术中清扫淋巴结数目、术后并发症总发生率、术后2年总生存率比较,差异无统计学意义(P>0.05)。

结论

相较于完全头侧入路,腹腔镜下结肠癌根治术经头尾侧联合入路能缩短手术时间、减少术中出血量、降低血管损伤风险,而完全头侧入路与头尾侧联合入路治疗结肠癌的安全性和近中期预后相当。

Objective

To investigate the short and medium term efficacy of laparoscopic radical resection of right half colon cancer by combined head and tail approach.

Method

Data of 99 patients with right half colon cancer who underwent laparoscopic radical resection from August 2018 to August 2021 were retrospectively analyzed, and divided into a cephalic group (n=49 cases, all cephalic approach) and a combined group (n=50 cases, combined cephalic and caudal approach) according to different approaches.SPSS 25.0 software was used to process the data.Measurement data such as surgery-related indicators and postoperative recovery indicators were represented by (x±s) and independent sample t test was used.The statistical data of complications and survival rate were expressed by[ cases (%)] using χ2 test.P<0.05 was considered statistically significant.

Results

The operative time of the combined group was shorter than that of the cephalic group,and the number of intraoperative blood loss and vascular injury cases was lower than that of the cephalic group(P<0.05).There was no significant difference in the time of first discharge, first feeding, drainage tube removal and hospital stay between the two groups (P>0.05).There was no significant difference in the number of lymph nodes removed during operation, the total incidence of postoperative complications and the 2-year overall survival rate between the two groups (P>0.05).

Conclusion

Compared with the complete cephalic approach,the combined cephalic and caudal laparoscopic radical resection of colon cancer can shorten the operation time,reduce the amount of intraoperative blood loss, and reduce the risk of vascular injury.The safety and nearmedium term prognosis of the combined cephalic and caudal approach for colon cancer are comparable.

表1 两组腹腔镜结肠癌根治术患者基线资料比较
表2 两组腹腔镜下结肠癌根治术患者围手术期相关指标比较
表3 两组腹腔镜下结肠癌根治术患者术后恢复指标比较(± s
表4 两组腹腔镜下结肠癌根治术患者术后并发症发生率比较[例(%)]
[1]
李乐平, 靖昌庆, 连国栋.中国腹腔镜结肠癌手术20年发展、问题与对策[J/CD].中华普外科手术学杂志(电子版), 2021,15(05): 477-481.
[2]
Kim HJ, Park JW.Surgical outcomes of various surgical approaches for transverse colon cancer [J].J Minim Invasive Surg, 2022, 25(1): 1-6.
[3]
熊文俊, 朱晓峰, 刘阳文, 等.尾内侧入路联合中间翻页式淋巴结清扫腹腔镜右半结肠癌根治术疗效观察[J].中华胃肠外科杂志, 2021, 24(03): 272-276.
[4]
杨熙华, 罗吉辉, 肖方涛, 等.头尾侧联合入路腹腔镜右半结肠癌根治术的近期临床疗效分析[J].中国普通外科杂志,2020, 29(04): 391-399.
[5]
潘海华, 童锋, 卫华松, 等.头尾侧联合入路在腹腔镜下D3淋巴结廓清术治疗右半结肠癌中的临床效果[J].浙江医学,2023, 45(14): 1541-1545.
[6]
中华人民共和国卫生和计划生育委员会医政医管局, 中华医学会肿瘤学分会.中国结直肠癌诊疗规范(2017年版) [J].中华外科杂志, 2018, 56(04): 241-258.
[7]
冯波, 钟昊, 张森, 等.腹腔镜右半结肠癌根治术切除范围争议与共识[J].中国实用外科杂志, 2023, 43(10): 1144-1146.
[8]
袁浩, 徐通海, 贾贵清, 等.改良腹腔镜辅助右半结肠癌D3根治术头侧入路疗效评价[J].四川医学, 2020, 41(01): 74-78.
[9]
Maatouk M, Safta YB, Kbir GH, et al.Caudal-to-Cranial Approach for Right Colectomy with Complete Mesocolic Excision in Colon Cancer:A Systematic Review and Meta-analysi[sJ].J Gastrointest Cancer, 2023, 54(3): 739-750.
[10]
王枭杰, 郑志芳, 池畔, 等.右原始后腹膜在右半结肠癌完整结肠系膜切除术中的解剖学观察和临床意义[J].中华胃肠外科杂志, 2021, 24(08): 704-710.
[11]
Koyama M, Miyagawa Y, Kitazawa M, et al.Laparoscopic right hemicolectomy with a cranial-first approach for right-sided colon cancer[ J].Tech Coloproctol, 2022, 26(11): 919-920.
[12]
鲍新民, 王日玮, 张开华, 等.腹腔镜下头尾侧联合入路治疗右半结肠癌的疗效分析[J].肿瘤防治研究, 2020, 47(11):856-860.
[13]
刘郁, 段绍斌.腹腔镜下头尾结合入路与完全头侧入路手术治疗右半结肠癌的临床疗效对比[J].中国普通外科杂志,2021, 30(04): 488-492.
[14]
于鹏, 段绍斌.三种不同手术入路在腹腔镜右半结肠癌根治术中的应用[J].现代消化及介入诊疗, 2022, 27(06): 692-696.
[15]
范增鹏, 黄敬敏, 周堤侠, 等.头侧-尾侧-中间入路行腹腔镜右半结肠癌根治术的临床3年随访研究[J/CD].中华普外科手术学杂志(电子版), 2021, 15(03): 287-289.
[16]
Yao Z, Wang X, Zhang Y, et al.Cranial-caudal-medial approach,counterclockwise complete mesocolic excision in laparoscopic right hemicolectomy[ J].Colorectal Dis, 2022, 24(10): 1258-1259.
[1] 肖建, 肖天保, 陈江, 杨桃, 何峰, 保甜甜, 曹一波, 杨琴, 赵颖. 吲哚菁绿成像技术在保留左结肠动脉的直肠癌根治术中的应用价值[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(02): 134-137.
[2] 金芳, 徐东飞, 尚培中, 张伟, 葛艳丽, 李晓英, 苗建军, 郭伟林. 腹腔镜直肠癌Dixon手术选择性应用超声刀和电钩的效果评价[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(02): 142-145.
[3] 周丽君, 王露, 林巧. 腹腔镜与开腹直肠癌切除术治疗中低位直肠癌的疗效及并发症对比[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(02): 146-148.
[4] 何可可, 顾海扬, 肖姝, 韦琪, 李鑫玉. 腹腔镜保留回盲部右半结肠切除术治疗右半结肠癌的临床效果研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(02): 149-152.
[5] 汪鑫, 向涵, 张伟. T型线联合超微创钳辅助经脐单孔腹腔镜胆囊切除术[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(02): 133-133.
[6] 燕速, 霍博文. 腹腔镜食管胃结合部腺癌根治性切除术[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 13-13.
[7] 冯帆, 马文亮, 董翔, 潘骏, 甘卫东, 郭宏骞. 前后结合入路机器人辅助根治性前列腺切除术早期疗效分析[J/OL]. 中华腔镜泌尿外科杂志(电子版), 2025, 19(01): 83-87.
[8] 王庆亮, 党兮, 师凯, 刘波. 腹腔镜联合胆道子镜经胆囊管胆总管探查取石术[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(02): 313-313.
[9] 杨建辉, 段文斌, 马忠志, 卿宇豪. 腹腔镜下脾部分切除术[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(02): 314-314.
[10] 叶劲松, 刘驳强, 柳胜君, 吴浩然. 腹腔镜肝Ⅶ+Ⅷ段背侧段切除[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(02): 315-315.
[11] 伊力扎提·阿扎提, 吐尔洪江·吐逊. 腹腔镜活体供肝切取术的临床现状[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(01): 30-35.
[12] 马子慧, 郭卫星. 腹腔镜肝尾状叶切除术的临床应用[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(01): 36-40.
[13] 栾天继, 曹定, 梅洪亮, 付航玮, 杨凯, 王丹, 尚作宏, 凌锋, 李支会, 张振雨, 胡逸林. 腹腔镜左半肝切除联合左肝管残端胆管探查取石治疗复杂肝左叶胆管结石合并胆总管结石患者疗效分析[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(01): 81-86.
[14] 邱枫, 杨天池, 韩威. 腹腔镜超声引导下射频消融治疗肝脏恶性肿瘤的安全性与疗效分析[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(01): 102-106.
[15] 戴勇. 腹腔镜扩大左半结肠切除术(附视频)[J/OL]. 中华结直肠疾病电子杂志, 2025, 14(01): 82-82.
阅读次数
全文


摘要