探讨甲状腺乳头状癌（PTC）尿碘水平与患者术后复发危险度分层的关系。

收集2017年1月至2020年12月期间接受手术治疗的500例PTC患者临床资料，统计患者术前检测尿碘水平及术后复发危险度分层，并根据患者术后3年内复发情况分为复发组（n=18）与未复发组（n=482），采用统计学软件SPSS 25.0分析数据，用Kendall's tau-b相关性检测术前尿碘水平与PTC复发危险度分层的关系；绘制ROC曲线分析术前尿碘水平对PTC患者术后复发的预测价值。P<0.05表示差异有统计学意义。

500例PTC患者低危层312例，中危层142例，高危层46例；尿碘水平：高危组>中危组>低危组（P<0.05）；Kendall's tau-b相关性分析显示，尿碘水平与甲状腺乳头状癌复发危险度分层呈正相关（r=0.135，P<0.05）；500例PTC患者术后随访期间复发18例，复发组患者淋巴结转移占比及促甲状腺激素（TSH）、甲状腺免疫球蛋白（Tg）、抗甲状腺球蛋白抗体（TgAb）、尿碘水平均高于未复发组（P<0.05）；ROC曲线结果显示，术前尿碘水平预测PTC患者术后复发的AUC>0.7，具有一定预测价值。

术前尿碘水平与PTC患者复发密切相关，在PTC患者复发预测中具有一定价值。

To investigate the relationship between urinary iodine level and stratified risk of recurrence in patients with papillary thyroid carcinoma (PTC).

Clinical data of 500 patients with PTC who received surgical treatment from January 2017 to December 2020 were collected. Preoperative urinary iodine level and postoperative recurrence risk of patients were statistically stratified, and patients were divided into recurrence group and non-recurrence group according to the recurrence situation within 3 years after surgery. Statistical software SPSS 25.0 was used to analyze the data. Kendall's tau-b correlation was used to detect the stratified relationship between preoperative urinary iodine level and the risk of PTC recurrence. ROC curve was drawn to analyze the predictive value of preoperative urinary iodine level for postoperative recurrence in PTC patients. P<0.05 indicated that the difference was statistically significant.

Among the 500 PTC patients, 312 cases were in low-risk layer, 142 cases were in middle-risk layer, and 46 cases were in high-risk layer. Urinary iodine level: high-risk group > medium-risk group > low-risk group (P<0.05); Kendall's tau-b correlation analysis showed that urinary iodine level was positively correlated with the risk of thyroid papillary carcinoma recurrence stratification (r=0.135，P<0.05). In the 500 PTC patients, 18 cases recurred during the follow-up. The lymph node metastasis ratio, thyroid stimulating hormone (TSH), thyroid immunoglobulin (Tg), anti-thyroglobulin antibody (TgAb) and urinary iodine levels in the recurrent group were higher than those in the non-recurrent group (P<0.05). ROC curve results showed that preoperative urinary iodine level predicted the AUC of postoperative recurrence in PTC patients to be greater than 0.7, which had certain predictive value.

Preoperative urinary iodine level is closely related to the recurrence of PTC patients, and has certain value in predicting the recurrence of PTC patients.