Laparoscopic pancreaticoduodenectomy (LPD) is regarded as a highly demanding procedure in pancreatic surgery due to its complexity and high risk of bleeding. Its safe implementation relies on precise preoperative evaluation, meticulous intraoperative manipulation, and standardized perioperative management. This paper systematically analyzes the key technical difficulties and surgical quality control points of LPD in China, and explores strategies for improvement. Preoperative evaluation generally includes resectability assessment and oncological evaluation. In addition to routine and accurate contrast-enhanced abdominal computed tomography (CT) and three-dimensional vascular reconstruction for assessing resectability and formulating surgical plans, rigorous monitoring of tumor marker levels is also of great significance for improving patient prognosis.

Furthermore, an appropriate surgical approach should be selected according to the tumor location and its relationship with major blood vessels; if necessary, a combination of multiple approaches can be adopted to complete the operation. Indications for vascular resection and reconstruction as well as arterial sheath dissection must be strictly followed, and these procedures should be performed by an experienced pancreatic surgery team. In addition, the method of pancreaticojejunostomy should be individualized based on the diameter of the pancreatic duct and the texture of the pancreatic parenchyma, with the placement of a pancreatic stent to reduce the risk of pancreatic fistula. Postoperative management involves monitoring of drainage fluid, precise treatment of complications such as pancreatic fistula and bleeding, and early removal of drainage tubes when conditions permit, in line with the concept of enhanced recovery after surgery (ERAS).

In the future, with the continuous development of intraoperative navigation technology and artificial intelligence, LPD is expected to achieve standardized and modularized operations, further improving its safety. Surgical robotics will also be one of the directions for the reform and development of pancreatic surgery in China in the next generation.