Abstract:
Objective By comparing the correlation between the surgery for adhesive small intestinal obstruction and SIRS test results, to provide a theoretical basis for the treatment of adhesive small bowel obstruction.
Methods A total of 106 patients with adhesive small bowel obstruction who were admitted to our hospital from January 2015 to January 2018 were selected as subjects. According to the treatment, 58 cases were divided into surgical treatment group and 48 cases were divided into non-surgical treatment group. SPSS21.0 was used for statistical analysis. The positive SIRS factor of the two groups was compared withχ2 test. The patients’ heart rate, body temperature, respiration, white blood cell count, tumor necrosis factor a (TNF-α), interleukin 2 (IL-2), interleukin-6 (IL-6), interleukin-8 (IL-8) and endotoxin levels were recorded and compared with independent t test. P<0.05 was considered as significant difference.
Results The number of white blood cell counts and days of non-surgical treatments in the surgical group was significantly higher than those in the non-surgical group (P<0.05). The number of positive parameters in SIRS factor of the two groups was closely related to surgery (P<0.05). Regression analysis showed that when the positive parameters in SIRS factor added one item, the risk of surgery added 2.565 times; the positive rate of SIRS factorin the surgery group was significantly higher than the non-surgical groups (P<0.05), regression analysis showed that the opportunities for surgery of positive of SIRS detection cases was 3.558 times than the negative cases; after treatment, the expression levels of TNF-α, LPS, IL-8, IL-6 were decreased, the expression levels of IL-2 was increased in both of the two groups. After surgery, the expression levels of TNF-α, IL-2, IL-6, IL-8 and endotoxin were significantly different (P<0.05).
Conclusion The SIRS factor can be used as a predictor of whether the surgical treatment is needed for patients with adhesive small bowel obstruction.
Key words:
Intestinal obstruction,
Tissue adhesions,
Systemic inflammatory response syndrome,
Regression analysis
Hua Wang, Wenyu Li. Correlation analysis of surgery for adhesive small intestinal obstruction and SIRS factor[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2019, 13(01): 61-64.