To comprehensively evaluate the research status and development trends of enteral immunonutrition support in patients with gastrointestinal malignant tumors through bibliometric methods, and to provide a reference basis for clinical practice and further research.

Literatures related to enteral immunonutrition in patients with gastrointestinal malignant tumors were retrieved from the Web of Science Core Collection database, and visualized analysis was performed using VOSviewer and CiteSpace.

A total of 373 studies were included in this paper, and the number of publications showed an increasing trend. There were 2 041 authors involved in research in the field of enteral immunonutrition for gastrointestinal tumors, among whom the authors with the most publications were Braga M (14 articles) and Gianotti L (14 articles) from Italy. China (81 articles, 21.7%), the United States (57 articles, 15.3%), and Japan (49 articles, 13.1%) were the leading countries in publishing research in this field. The main research institutions included the University of Milan, Jagiellonian University, and Nanjing University. Clinical Nutrition was the journal with the most published literatures in this field. Keyword analysis showed a total of 4 clusters, and the hot research fields included "supplementation of ω-3 fatty acids", "enteral immunonutrition and complications", "surgical resection and early enteral nutrition supplementation", and "use of immunonutrition in patients with gastrointestinal tumors". On this basis, studies on the effect of immunonutrition support in improving the nutritional status, clinical outcomes, and quality of life of patients with gastrointestinal tumors have received more extensive attention.

The field of enteral immunonutrition support in patients with gastrointestinal malignant tumors is in a stage of development. Future research should focus on exploring the potential role of enteral immunonutrition in improving the clinical outcomes and quality of life of such patients, so as to provide a more solid scientific basis for clinical practice.