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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2022, Vol. 16 ›› Issue (01): 59-62. doi: 10.3877/cma.j.issn.1674-3946.2022.01.018

• Original Article • Previous Articles     Next Articles

The prelim inary study on Porcine Fibrin Sealant used in closing the mesocolon hiatus after colorectal resection

Wei Cui1, Tao Li1, Gang Chen1, Shiyong Li1,()   

  1. 1. Medical Department of General Surgery; the 1st Medical Center of PLA General Hospital, Beijing 100853, China
  • Received:2021-11-18 Online:2022-02-26 Published:2022-02-12
  • Contact: Shiyong Li
  • Supported by:
    Military logistics scientific research project(CLJ17J022)

Abstract:

Objective

To study the clinical effect of Porcine Fibrin Sealant used in closing the mesocolon hiatus after colorectal resection.

Methods

The 120 cases of sigmoid colon and rectal cancer treated in our hospital from Jan 2018 to Dec 2020 were analyzed. They were randomly divided into experimental group and control group,each 60 cases. The Porcine Fibrin Sealant was used to close the mesocolon hiatus after colorectal resection in the experimental group while the spiral PGA-PCL in control group. Statistical software SPSS 11.5 was used for analysis. The perioperative measurement data of the two groups were presented as(

xˉ
±s),and compared with independent t test. The postoperative complications were determined by χ2 test. P<0.05 was considered statistically significant.

Results

The closing time,volume of drainage within 72 hours after operation were significantly lower in the experimental group than control group(P<0.05). No significant difference was noted between the two groups in terms of the length of mesocolon hiatus,blood loss,dissected lymph nodes,first exhaust time(P>0.05). Furthermore,there were no significant difference in the postoperative complications(P>0.05).

Conclusions

Closing the mesocolon hiatus after colorectal resection with Porcine Fibrin Sealant is easy and safe,which is worthy of clinical promotion.

Key words: Fibrin tissue adhesive, Colorectal resection, Mesocolon hiatus

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