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Chinese Journal of Operative Procedures of General Surgery(Electronic Edition) ›› 2020, Vol. 14 ›› Issue (05): 480-482. doi: 10.3877/cma.j.issn.1674-3946.2020.05.015

Special Issue:

• Original Article • Previous Articles     Next Articles

The clinical value of MRI combined with mammography in the diagnosis of ductal carcinoma in situ

Chengxu Tang1,(), Wenlong Chen1, Rui Yang2   

  1. 1. Department of Radiology, Zhongda Hospital of Southeast university (Jiangbei District), Jiangsu 210048, China
    2. Central Laboratory of Wuxi Hospital, Nanjing Medical University, Jiangsu 214000, China
  • Received:2019-10-30 Online:2020-10-26 Published:2020-10-26
  • Contact: Chengxu Tang
  • About author:
    Corresponding author: Tang Chengxu, Email:
  • Supported by:
    National natural science foundation of China (youth project) ,(81602728)

Abstract:

Objective

To investigate the clinical value of MRI combined with mammography in the diagnosis of mammary ductal carcinoma in situ.

Methods

From February 2018 to February 2019, 90 patients with mammary ductal carcinoma in situ were enrolled in to present study. All the patients received both mammography and MRI examinations of the mammary gland, and the diagnostic value of combined examinations was evaluated. Statistical analysis were performed by using SPSS 22.0 software. Measurement data such as age and lesion diameter were expressed as (±s) and were examined by using t test. Pathological diagnosis was used as the gold standard to analyze the sensitivity and specificity of MRI and combined diagnosis. Count data were expressed as n(%), and were examined by using χ2 test, A P value <0.05 was considered as statistically significant.

Results

All of 90 patients with breast ductal carcinoma in situ had a single lesion, including 48 malignant lesions, and 42 benign lesions. There was no significant difference of age between patients with malignant lesions and benign lesions (P>0.05). The diameter of benign lesions was lower than that of malignant lesions, with significant difference (P<0.05). Taking the pathological diagnosis results as the gold standard, the sensitivity and specificity of MRI combined with mammography mammography targets were 91.67% and 90.48% respectively, which were higher than 75.00% and 71.43% of MRI alone and 66.67% and 64.29 of mammography alone respectively, with significant difference (P<0.05).

Conclusion

MRI combined with mammography has high sensitivity and specificity in the diagnosis of mammary ductal carcinoma in situ, which could provide scientific basis for clinical diagnosis and judgment.

Key words: Carcinoma, ductal, breast, Magnetic resonance imaging, Diagnosis, Mammography, Clinical value

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