To evaluate the recent and long-term effects of anatomical hepatectomy and non-anatomical hepatectomy for regional hepatolithiasis.

Retrospective analysis of forty hospitalized anatomical hepatectomy patients and forty-six non-anatomical hepatectomy patients from June 2013 to June 2015. Statistical analysis was performed by using SPSS19.0 software. Measurement data were expressed as and were compared by student’s t test, the recurrence rate of the stones was calculated according to kaplan-meier method to drawn the survival curve, and the survival rate was compared with the Log-rank test. Post-operative complication rate was compared by chi-square test. P less than 0.05 was considered as significant difference.

The intra-operative blood, hospital stays postoperative biliary leakage, surface infection and recurrence of stones in anatomical hepatectomy group were significantly less than the non-anatomical hepatectomy group, the difference was statistically significant (P<0.05). 86 patients were followed up for 24 months, one patient (2.5%) in the anatomical hepatectomy group had stone residue 13 months after surgery, while 18 patients (39.1%) in the non-anatomical hepatectomy group, the difference was statistically significant (P<0.05).

Anatomical hepatectomy which is in accordance with the physiological structure of the liver can reduce the intra-operative blood, hospital stays and prevent the recurrence of stones.