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中华普外科手术学杂志(电子版) ›› 2025, Vol. 19 ›› Issue (06) : 693 -697. doi: 10.3877/cma.j.issn.1674-3946.2025.06.026

论著

基于CiteSpace和VOSviewer对胃肠道恶性肿瘤患者肠内免疫营养支持的文献计量分析
王婷文1, 黄家晴1, 卞晓洁1,(), 陆晓峰2,(), 管文贤2   
  1. 1210008 南京,南京大学医学院附属鼓楼医院药学部
    2210008 南京,南京大学医学院附属鼓楼医院普通外科
  • 收稿日期:2024-11-07 出版日期:2025-12-26
  • 通信作者: 卞晓洁, 陆晓峰

Bibliometric analysis of enteral immunonutrition support in patients with gastrointestinal malignant tumors based on citeSpace and VOSviewer

Tingwen Wang1, Jiaqing Huang1, Xiaojie Bian,1(), Xiaofeng Lu,2(), Wenxian Guan2   

  1. 1Department of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing Jiansu Province 210008, China
    2Department of General Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing Jiansu Province 210008, China
  • Received:2024-11-07 Published:2025-12-26
  • Corresponding author: Xiaojie Bian, Xiaofeng Lu
引用本文:

王婷文, 黄家晴, 卞晓洁, 陆晓峰, 管文贤. 基于CiteSpace和VOSviewer对胃肠道恶性肿瘤患者肠内免疫营养支持的文献计量分析[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(06): 693-697.

Tingwen Wang, Jiaqing Huang, Xiaojie Bian, Xiaofeng Lu, Wenxian Guan. Bibliometric analysis of enteral immunonutrition support in patients with gastrointestinal malignant tumors based on citeSpace and VOSviewer[J/OL]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2025, 19(06): 693-697.

目的

通过文献计量学方法全面评估胃肠道恶性肿瘤患者肠内免疫营养支持的研究现状和发展趋势,为临床实践及下一步研究提供参考依据。

方法

在Web of Science核心数据库中检索胃肠道恶性肿瘤患者肠内免疫营养相关文献,使用VOSviewer和CiteSpace进行可视化分析。

结果

共纳入373篇研究,发文量呈增长趋势。有2 041名作者参与胃肠道肿瘤肠内免疫营养领域研究,其中发文量最多的作者是意大利的Braga M(14篇)和Gianotti L(14篇)。中国(81篇,21.7%)、美国(57篇,15.3%)和日本(49篇,13.1%)是该领域研究发表的主导国家,主要研究机构有米兰大学、雅盖隆大学和南京大学。Clinical Nutrition是刊载文献最多的期刊。关键词分析共有4个聚类,热点研究领域包括"ω-3脂肪酸的补充"、"肠内免疫营养与并发症"、"外科手术切除与早期肠内营养补充"以及"胃肠道肿瘤患者免疫营养的使用",在此基础上,有关免疫营养支持对改善胃肠道肿瘤患者营养状况、临床结局和生存质量的效果相关研究受到更广泛关注。

结论

胃肠道恶性肿瘤患者肠内免疫营养支持领域正处于发展阶段,未来研究应聚焦于探索肠内免疫营养对改善此类患者临床结局及生存质量的潜在作用,为临床实践提供更为坚实的科学依据。

Objective

To comprehensively evaluate the research status and development trends of enteral immunonutrition support in patients with gastrointestinal malignant tumors through bibliometric methods, and to provide a reference basis for clinical practice and further research.

Methods

Literatures related to enteral immunonutrition in patients with gastrointestinal malignant tumors were retrieved from the Web of Science Core Collection database, and visualized analysis was performed using VOSviewer and CiteSpace.

Results

A total of 373 studies were included in this paper, and the number of publications showed an increasing trend. There were 2 041 authors involved in research in the field of enteral immunonutrition for gastrointestinal tumors, among whom the authors with the most publications were Braga M (14 articles) and Gianotti L (14 articles) from Italy. China (81 articles, 21.7%), the United States (57 articles, 15.3%), and Japan (49 articles, 13.1%) were the leading countries in publishing research in this field. The main research institutions included the University of Milan, Jagiellonian University, and Nanjing University. Clinical Nutrition was the journal with the most published literatures in this field. Keyword analysis showed a total of 4 clusters, and the hot research fields included "supplementation of ω-3 fatty acids", "enteral immunonutrition and complications", "surgical resection and early enteral nutrition supplementation", and "use of immunonutrition in patients with gastrointestinal tumors". On this basis, studies on the effect of immunonutrition support in improving the nutritional status, clinical outcomes, and quality of life of patients with gastrointestinal tumors have received more extensive attention.

Conclusion

The field of enteral immunonutrition support in patients with gastrointestinal malignant tumors is in a stage of development. Future research should focus on exploring the potential role of enteral immunonutrition in improving the clinical outcomes and quality of life of such patients, so as to provide a more solid scientific basis for clinical practice.

图1 胃肠道恶性肿瘤患者肠内免疫营养研究的发文量
图2 国家发文情况可视化图谱
表1 胃肠道肿瘤患者肠内免疫营养补充领域发文量排名前10的国家、机构
图3 机构发文情况可视化图谱
表2 胃肠道恶性肿瘤肠内免疫营养支持相关研究排名前10的期刊
表3 发表文章数量排名前14位的核心作者
图4 (A)胃肠道恶性肿瘤肠内免疫营养支持关键词共现图谱;(B)胃肠道恶性肿瘤肠内免疫营养支持关键词共现时间线图
图5 被引用次数排名前18的关键词突现图谱
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