探究腹腔镜完全经腹膜外疝修补术（TEP）中轻量聚丙烯补片与自固定补片的临床效果。

采用前瞻性队列研究，选取2022年3月至2024年3月男性腹股沟疝患者120例，根据其TEP中应用补片的不同，将其分为聚丙烯组（n=58）和自固定组（n=62），采用SPSS 27.0统计学软件分析数据，用t检验和重复测量设计方差分析比较两组患者临床资料、手术指标、手术前后视觉模拟评分法（VAS）评分、术后并发症及随访期间复发情况，检验水准α=0.05。

两组患者临床资料差异无统计学意义。聚丙烯组手术时间长于自固定组，治疗费用低于自固定组，差异具有统计学意义（t=2.063、10.406，P均<0.05）。两组患者术后 VAS 评分均随时间显著降低，组内不同时间点的差异均具有统计学意义（F_时间=290.688，P<0.05）。自固定补片组整体 VAS 评分低于聚丙烯组，该组别间主效应差异具有统计学意义（F_分组=13.318，P<0.05）。同时，两组 VAS 评分随时间变化的趋势存在差异，时间 × 组别的交互效应具有统计学意义（F_交互=4.382，P<0.05），两组患者术后1个月和2个月VAS评分差异均具有统计学意义（P<0.05），术后并发症及随访期间复发情况差异无统计学意义（P>0.05）。

腹腔镜完全经腹膜外疝修补术（TEP）中，轻量聚丙烯补片与自固定补片术后并发症发生率及疝复发风险无差异，安全性相当。术中采用自固定补片患者手术时间短、术后疼痛程度轻，术中采用轻量聚丙烯补片价格更低。临床可结合患者自身条件，差异化选择补片。

To investigate the clinical efficacy of lightweight polypropylene mesh versus self-gripping mesh in laparoscopic totally extraperitoneal hernia repair (TEP).

A prospective cohort study was conducted. A total of 120 male patients with inguinal hernia treated from March 2022 to March 2024 were enrolled. Patients were divided into the polypropylene group (n=58) and the self-gripping group (n=62) according to the type of mesh used during TEP. Statistical analyses were performed via SPSS 27.0 software. The t test and repeated-measures analysis of variance were used to compare baseline clinical data, intraoperative parameters, pre- and postoperative Visual Analogue Scale (VAS) pain scores, postoperative complications and hernia recurrence during follow-up between the two groups. The significance level was set at (alpha=0.05).

No statistically significant differences were found in baseline clinical data between the two groups. The polypropylene group had longer operative time but lower total medical costs than the self-gripping group, with statistically significant differences (t=2.063), (t=10.406), all (P<0.05). Postoperative VAS pain scores of both groups decreased markedly over time, and the differences across time points within each group were statistically significant (F_time=290.688), (P<0.05). The overall VAS scores of the self-gripping mesh group were lower than those of the polypropylene group, and the main effect between groups was statistically significant (F_group=13.318), (P<0.05). In addition, the changing trends of VAS scores over time differed between the two groups, and the time-by-group interaction effect reached statistical significance (F_interaction=4.382), (P<0.05). Significant intergroup differences in VAS scores were detected at 1 month and 2 months after surgery (P<0.05). There were no statistical differences in postoperative complication rates or hernia recurrence rates during follow-up (P>0.05).

For laparoscopic totally extraperitoneal hernia repair (TEP), lightweight polypropylene mesh and self-gripping mesh demonstrate equivalent safety with no differences in postoperative complication rates or long-term hernia recurrence risks. The use of self-gripping mesh shortens operative duration and alleviates postoperative pain, whereas lightweight polypropylene mesh boasts a lower cost. Clinicians may select mesh products individually based on each patient's actual situation.