研究术中超声联合细针穿刺定位在乳腺微小病灶切除中的临床应用效果。

回顾性分析2020年11月至2021年11月治疗的96例临床触诊阴性乳腺微小病灶（<1 cm）患者资料，根据病灶定位方式不同分为对照组（n=54例，采用常规术前超声检查体表标记定位切除病灶）和实验组（n=42例，采用术中超声联合细针穿刺定位切除病灶）。采用软件SPSS 25.0分析数据，手术相关指标、术后24 h疼痛评分（VAS）等计量资料以（）表示，采用独立样本t检验；术后并发症及复发情况等计数资料比较采用χ²或Fisher检验。P<0.05为差异有统计学意义。

实验组患者手术时间、切除组织体积、住院时间及术后24 h VAS评分优于对照组（P<0.05）；实验组患者术后未见皮下血肿、切口感染发生，并发症发生率低于对照组（0% vs. 13.0%），差异有统计学意义（χ²=4.112，P=0.043）；实验组患者术后门诊复查超声未见原病灶残留，术后6个月及1年，两组患者复发率比较差异均未见统计学意义（P>0.05）。

乳腺微小病灶切除术中应用超声联合细针穿刺定位能有效切除病灶，缩短手术时间，减少正常乳腺组织损伤，手术创伤小，患者术后疼痛轻，并发症少，安全可行，值得临床推广应用。

To investigate the clinical effect of intraoperative ultrasound combined with fine needle aspiration in the resection of breast microlesions.

The data of 96 patients with clinically palpated negative breast small lesions (<1 cm) treated from November 2020 to November 2021 were retrospectively analyzed, and divided into control group (n=54 cases, resection of lesions by routine preoperative ultrasonography with body surface markers) and experimental group (n=42 cases, resection of lesions) according to different localization methods. Intraoperative ultrasound combined with fine needle puncture was used to locate the lesion. SPSS 25.0 software was used to analyze the data. Surgical indicators, pain score (VAS) 24 hours after surgery and other measurement data were expressed as (), and independent sample t test was used. The statistical data of postoperative complications and recurrence were compared by χ² or Fisher test. P<0.05 was considered statistically significant.

The operative time, resected tissue volume, hospital stay and 24 h VAS scores of the experimental group were better than those of the control group (P<0.05). No subcutaneous hematoma or incision infection was observed in the experimental group, and the complication rate was lower than that in the control group (0% vs. 13.0%), the difference was statistically significant (χ²=4.112, P=0.043). In the experimental group, no residual original lesion was found by ultrasonography in the outpatient department after surgery, and there was no significant difference in recurrence rate between the two groups at 6 months and 1 year after surgery (P>0.05).

The application of ultrasound combined with fine needle puncture localization in the resection of breast microfocal lesions can effectively remove the lesions, shorten the operation time, reduce the damage of normal breast tissue, and reduce the surgical trauma, postoperative pain and complications, which is safe and feasible, worthy of clinical promotion and application.