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中华普外科手术学杂志(电子版) ›› 2023, Vol. 17 ›› Issue (01) : 110 -113. doi: 10.3877/cma.j.issn.1674-3946.2023.01.028

综述

脾切除术后门静脉血栓形成及其机制的研究进展
耿志达1, 俞星新1, 刘雨1, 梁英健1,()   
  1. 1. 150000 哈尔滨,哈尔滨医科大学附属第一医院肝脏外科
  • 收稿日期:2022-01-10 出版日期:2023-02-26
  • 通信作者: 梁英健

Research progress on portal vein system thrombosis and its mechanism after splenectomy

Zhida Geng1, Xingxin Yu1, Yu Liu1, Yingjian Liang1,()   

  1. 1. Department of Liver Surgery,The First Clinical Hospital affiliated to Harbin Medical University,Harbin Heilongjiang Province 150000,China
  • Received:2022-01-10 Published:2023-02-26
  • Corresponding author: Yingjian Liang
引用本文:

耿志达, 俞星新, 刘雨, 梁英健. 脾切除术后门静脉血栓形成及其机制的研究进展[J/OL]. 中华普外科手术学杂志(电子版), 2023, 17(01): 110-113.

Zhida Geng, Xingxin Yu, Yu Liu, Yingjian Liang. Research progress on portal vein system thrombosis and its mechanism after splenectomy[J/OL]. Chinese Journal of Operative Procedures of General Surgery(Electronic Edition), 2023, 17(01): 110-113.

门静脉血栓形成(PVST)是脾切除术后最常见的并发症之一,其术后血栓形成及机制至今未明确。目前我们已经确定了脾切除术后PVST的几个系统性和局部性危险因素。系统性危险因素包括血液病、恶性肿瘤等。局部危险因素主要与脾脏特征有关,如脾脏重量和脾静脉直径。脾切除术后PVST发生的具体机制仍在研究中,本文旨在通过血流动力学的紊乱、血液的高凝状态、血管内皮的损伤(Virchow三联征)方面来探究脾切除术后PVST发生机制及治疗。

Portal vein thrombosis(PVST)is one of the most common complications after splenectomy. We have identified several systemic and local risk factors for PVST after splenectomy. Systemic risk factors include hematopathy,malignancy,etc. Local risk factors are mainly related to splenic features such as spleen weight and splenic vein diameter. The specific mechanism of PVST after splenectomy is still under investigation. We want to explore the mechanism and treatment of PVST after splenectomy from the aspects of hemodynamic disorder,blood hypercoagulability,and vascular endothelial injury(Virchow triad).

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